I am easily irritated when it comes to characters, but here's my list anyway ^^
1. Mokona from xxxHolic: He's just more irritating than the other one… I can stand the white one because he's kinda cute, the other one seems like he was born to be a puffy thorn in everyone's side.
2. Misa-Misa: Other than huge Death Note fans (maybe even some of them o.o) she's just plain irritating… Like all the really dumb stereotype cheerleaders the comedy world has come to know and despise.
3. Naruto: Naruto fans, please don't kill me… He's just –shudders- EVERYWHERE O.O I saw him on a business card for a Ramen place, I mean honestly. Do we NEED to associate Ramen with Naruto? I'm really happy Maruchan has no plans on changing their logo since we'd probably see the headband or something.
4. (not sure if this applies but) Voldo from Soul Calibur: Am I the only person freaked out by this guy? I mean, he does the worm then practically dry humps (excuse the content ^^'') you to slice you a few times with freaky claw things. Does he think he's John Travolta, or other random disco dancer, with the way he doges… it's just… Creepy ~.~
5. Farfello from Weiss Kruez: If you even lay eyes on this guy, he looks creepy. But then his personality makes you want hit him repeatedly with a golf club until he stops moving. Then again, he might like that ~.~ All the members of his team have these awesome abilities, like Telekinesis, reading minds, and can see the future, what's his? He can't feel pain because he tormented himself in his youth. Simply makes my eye twitch.
That is all for now >:3